Publications


Rosenberg BR, Dewell S, Papavasiliou FN. 2011.
Identifying mRNA Editing Deaminase Targets by RNA-Seq.
RNA and DNA Editing: Methods and Protocols (R. Aphasizhev, Editor). Springer Protocols - Humana Press; ISBN-10: 1617790176. [PDF]    |    [Amazon Books]

Rosenberg BR, Hamilton CE, Mwangi MM, Dewell S, Papavasiliou FN. 2011.
Transcriptome-wide sequencing reveals numerous APOBEC1 mRNA-editing targets in transcript 3' UTRs.
Nat Struct Mol Biol. 18(2):230-6. [PDF]

Sebastian Fugmann, Marilyn Diaz and F. Nina Papavasiliou, Editors. 2010.
DNA deamination and the Immune System.
Series on Molecular Medicine, volume 3. London, UK, Imperial College Press, 2010. ISBN -101-84816-592-7. [Amazon.com]

Eric L. Fritz and F. Nina Papavasiliou. 2010.
Cytidine deaminases: AIDing DNA demethylation?
Genes Dev. 24:2107-2114. [PDF]

Pete Stavropoulos and F. Nina Papavasiliou. 2010.
Using T.brucei as a biological epitope display platform, to elicit specific antibody responses.
J Immunol Methods 362(1-2):190-4. [PDF]

Claire E. Hamilton, Nina F. Papavasiliou and Brad R. Rosenberg. 2010.
Diverse functions for DNA and RNA editing in the immune system.
RNA Biology 7:2, 1-10. [PDF]

Jan Davidson-Moncada, F. Nina Papavasiliou and Wayne Tam. 2009.
miRNAs of the Immune System: Roles in Inflammation and Cancer.
Annals of the New York Academy of Science 1183 (Issue: The Year in Immunology 2): 183-194. [PDF]

Wesley A. Dunnick, John T. Collins, Jian Shi, Gerwin Westfield, Clinton Fontaine, Paul Hakimpour, and F. Nina Papavasiliou. 2009.
Switch recombination and somatic hypermutation are controlled by the heavy chain 3' enhancer region.
J. Exp. Med. 206(12):2613-23. [PDF]

Grace Teng and F. Nina Papavasiliou. 2009.
Long noncoding RNAs: Implications for antigen receptor diversification.
Advances in Immunology 104: 25-50. [PDF]

Rebecca Delker, Sebastian Fugmann and F. Nina Papavasiliou. 2009.
A coming of age story: Activation-Induced Cytidine Deaminase turns 10.
Nature Reviews Immunology 10 (11): 1147-53. [PDF]

Catharine E. Boothroyd, Oliver Dreesen, Tatyana Leonova, K. Ina Ly, Luisa M. Figueiredo, George A. M. Cross & F. Nina Papavasiliou. 2009.
A yeast-endonuclease-generated DNA break induces antigenic switching in Trypanosoma brucei.
Nature doi:10.1038/nature07982. [PDF]    |    Plasmids used in this article are available through [Addgene]

Thanks to Seed Magazine [link], Cell [link] and Nature [link] for featuring this paper.

Grace Teng and F. Nina Papavasiliou. 2008.
Shhh! Silencing by microRNA-155.
Phil. Trans. R. Soc. B doi:10.1098/rstb.2008.0209. [PDF]

Grace Teng, Paul Hakimpour, Pablo Landgraf, Amanda Rice, Thomas Tuschl, Rafael Casellas, and F. Nina Papavasiliou. 2008.
MicroRNA-155 Is a Negative Regulator of Activation-Induced Cytidine Deaminase.
Immunity 28:621-629. [PDF]    |    Plasmids used in this article are available through [Addgene]

Thanks to Science [PDF] and Nature Reviews Immunology [PDF] for featuring this paper.

KW Gaston, MA Rubio, JL Spears, I Pastar, FN Papavasiliou and JD Alfonzo. 2007.
C to U editing at position 32 of the anticodon loop precedes tRNA 5' leader removal in trypanosomatids.
Nucl. Acids Research 35(20):6740-9. [PDF]


Grace Teng and F. Nina Papavasiliou. 2007.
Immunoglobulin Somatic Hypermutation.
Annu. Rev. Genet. 41:107-20. [PDF]


M.A.T. Rubio, I. Pastar, K.W. Gaston, F. Ragone, C. Janzen, G.A.M. Cross, F. N. Papavasiliou and J.D. Alfonzo. 2007.
An Adenosine to Inosine tRNA editing enzyme that can perform C to U deamination of DNA.
PNAS 104(19):7821-6. [PDF]    |    Plasmids used in this article are available through [Addgene]

E. Crouch, Z. Li, M Takizawa, P. Gourzi, L. Feigenbaum, S. Janz, FN Papavasiliou and R. Casellas. 2007.
Regulation of AID expression in the immune response.
J. Exp. Med. 204(5):1145-56. [PDF]


B. Rosenberg and Papavasiliou FN. 2007.
Beyond CSR and SHM: AID and related deaminases in host defence against viral infection.
Advances in Immunology 94:215-44. [PDF]


Polyxeni Gourzi, Tatyana Leonova, and F. Nina Papavasiliou. 2007.
Viral induction of AID is independent of the interferon and the Toll-like receptor signaling pathways but requires NFkB.
J. Exp. Med. 19;204(2):259-65. [PDF]

P. Gourzi, Leonova T, Papavasiliou FN. 2006.
A role for activation-induced cytidine deaminase in the host response against a transforming retrovirus.
Immunity 24(6):779-86. [PDF]

Thanks to Science [PDF] for featuring this paper.

E. Besmer , Market E, Papavasiliou FN. 2006.
The transcription elongation complex directs activation-induced cytidine deaminase-mediated DNA deamination.
Mol. Cell. Biol. 26(11):4378-85. [PDF]    |    Plasmids used in this article are available through [Addgene]

E. Besmer, P. Gourzi and F.N. Papavasiliou. 2004.
The Regulation of Somatic Hypermutation.
Current Opinion in Immunology. 16: 241-245. [PDF]

S.K. Dickerson, Eleonora Market, Eva Besmer, F.N. Papavasiliou. 2003.
AID mediates hypermutation by deaminating single stranded DNA.
J. Exp. Med. 197:1291-6. [PDF]    |    Plasmids used in this article are available through [Addgene]

S.K. Dickerson and F.N. Papavasiliou. 2003.
A modified digestion-circularization (dc)PCR approach to detect hypermutation-associated DNA double-strand breaks.
Ann. NY Acad. Sci. 987:135-9. [PDF]

E. Market and F.N. Papavasiliou. 2003.
V(D)J recombination and the Evolution of the adaptive immune system.
PloS Biology. 1: 13. [PDF]

F.N. Papavasiliou and D.G. Schatz. 2002.
Somatic Hypermutation: Merging mechanisms for Genetic Diversity.
Cell. 109: S1-S20. [PDF]